Synthesis of 4-substituted-1,2,3-triazole carbanucleoside analogues of ribavirin via click chemistry.
نویسندگان
چکیده
The synthesis and biological evaluation as antiviral agents of a series of racemic 4-aryl-1,2,3-triazolo-2',3'-dideoxy-2'-iodocarbanucleosides and 4-aryl-1,2,3-triazolo-2',3'-dideoxy-2',3'-didehydrocarbanucleosides is presented. These compounds were produced using a click chemistry approach, with the iodoazide 13a as the key intermediary.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 5 23 شماره
صفحات -
تاریخ انتشار 2007